Effects of maternal choline intake on placental gene expression - GSE39290
To explore the influence of maternal choline intake on placental gene expression, we employed whole genome microarray expression profiling to identify genes that were differentially expressed in placental tissues obtained from women consuming two different doses (480 vs. 930 mg/d) of choline throughout the third trimester of pregnancy. Healthy third trimester (gestational week 26-29) pregnant women were randomized to a 12-week choline controlled feeding study. The participants consumed either 480 (n=6) or 930 (n=6) mg choline/d. Full thickness placental samples were collected at delivery to extract RNA and perform the arrays.
--
Healthy third trimester (gestational week 26-29) pregnant women were randomized to a 12-week choline controlled feeding study. The participants consumed either 480 (n=6) or 930 (n=6) mg choline/d for 12 weeks. Placental samples were obtained at delivery
--
--
--
--
| Sample ID | !Sample_title | mode of delivery | tissue | gestational age at delivery | participants group |
|---|---|---|---|---|---|
| GSM960125 | L1-480choline | C-section | placenta | 40 | healthy third trimester (gestational week 26-29) pregnant women |
| GSM960126 | L2-480choline | vaginal | placenta | 40 | healthy third trimester (gestational week 26-29) pregnant women |
| GSM960127 | L3-480choline | vaginal | placenta | 40 | healthy third trimester (gestational week 26-29) pregnant women |
| GSM960128 | L4-480choline | vaginal | placenta | 41.6 | healthy third trimester (gestational week 26-29) pregnant women |
| GSM960129 | L5-480choline | vaginal | placenta | 41 | healthy third trimester (gestational week 26-29) pregnant women |
| File |
|---|
All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.
| Sample ID | !Sample Title | Mode of delivery | Tissue | Gestational age at delivery | Participants group | Gender of baby | Choline intake for 12 weeks |
|---|---|---|---|---|---|---|---|
| GSM960125 | L1-480choline |
C-section |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
female |
480 mg/d |
| GSM960126 | L2-480choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
480 mg/d |
| GSM960127 | L3-480choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
480 mg/d |
| GSM960128 | L4-480choline |
vaginal |
placenta |
41.6 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
480 mg/d |
| GSM960129 | L5-480choline |
vaginal |
placenta |
41 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
480 mg/d |
| GSM960130 | L6-480choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
480 mg/d |
| GSM960131 | H1-930choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
female |
930 mg/d for 12 wks |
| GSM960132 | H2-930choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
930 mg/d for 12 wks |
| GSM960133 | H3-930choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
female |
930 mg/d for 12 wks |
| GSM960134 | H4-930choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
930 mg/d for 12 wks |
| GSM960135 | H5-930choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
930 mg/d for 12 wks |
| GSM960136 | H6-930choline |
vaginal |
placenta |
40 |
healthy third trimester (gestational week 26-29) pregnant women |
male |
930 mg/d for 12 wks |
| Name | ||
|---|---|---|
| All Samples | Default | View |
| In order to make new Group Sets or change settings, please log in. | ||
| Group Set | |
|---|---|
| All Samples |