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Clinical

Placental gene expression in severe preeclampsia - GSE10588

Purpose

The series is composed of thirty hybridizations for analysis of differentially expressed genes in normal placenta tissues from patients with normal labor and placenta tissues from patients with severe preeclampsia. Patients tissues samples were obtained from (Vasilis. Total RNA extraction was performed by using the MagNa Pure Compact RNA Isolation Kit (Roche Applied Science).

Hypothesis

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Experimental Design

Twenty-six out of 50 normal placentas were randomly selected to match with 17 preeclamptic placentas, accounting for parity. Microarrays were performed applying a direct comparison design.

Experimental Variables

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Controls

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Methods

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Additional Information

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Microarray
ABI Human Genome Survey v2
43 Samples Loaded: 43
Human (Homo sapiens)
placenta
Pre-eclampsia
Sample Set Spreadsheet
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Samples Preview
Sample ID !Sample Title Group Placenta tissue
GSM225470 Placenta tissue from patient with normal labor, replicate 1 of 26 normal TRUE
GSM225471 Placenta tissue from patient with normal labor, replicate 2 of 26 normal TRUE
GSM225472 Placenta tissue from patient with normal labor, replicate 3 of 26 normal TRUE
GSM225473 Placenta tissue from patient with normal labor, replicate 4 of 26 normal TRUE
GSM225474 Placenta tissue from patient with normal labor, replicate 5 of 26 normal TRUE
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File
sampleset4000017_sampleannotations_group.csv
Sample Set Spreadsheet
sampleset4000017_sampleannotations_group.csv
Sample Set Spreadsheet
Raw Signal
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Sample ID !Sample Title Group Placenta tissue
GSM225470
Placenta tissue from patient with normal labor, replicate 1 of 26
normal
TRUE
GSM225471
Placenta tissue from patient with normal labor, replicate 2 of 26
normal
TRUE
GSM225472
Placenta tissue from patient with normal labor, replicate 3 of 26
normal
TRUE
GSM225473
Placenta tissue from patient with normal labor, replicate 4 of 26
normal
TRUE
GSM225474
Placenta tissue from patient with normal labor, replicate 5 of 26
normal
TRUE
GSM225475
Placenta tissue from patient with normal labor, replicate 6 of 26
normal
TRUE
GSM225476
Placenta tissue from patient with normal labor, replicate 7 of 26
normal
TRUE
GSM225477
Placenta tissue from patient with normal labor, replicate 8 of 26
normal
TRUE
GSM225478
Placenta tissue from patient with normal labor, replicate 9 of 26
normal
TRUE
GSM225479
Placenta tissue from patient with normal labor, replicate 10 of 26
normal
TRUE
GSM225480
Placenta tissue from patient with normal labor, replicate 11 of 26
normal
TRUE
GSM225481
Placenta tissue from patients with severe preeclampsia, replicate 1 of 17
preeclampsia
TRUE
GSM225483
Placenta tissue from patient with normal labor, replicate 12 of 26
normal
TRUE
GSM225484
Placenta tissue from patient with normal labor, replicate 13 of 26
normal
TRUE
GSM225485
Placenta tissue from patient with normal labor, replicate 14 of 26
normal
TRUE
GSM225486
Placenta tissue from patient with normal labor, replicate 15 of 26
normal
TRUE
GSM225487
Placenta tissue from patient with normal labor, replicate 16 of 26
normal
TRUE
GSM225488
Placenta tissue from patient with normal labor, replicate 17 of 26
normal
TRUE
GSM225489
Placenta tissue from patient with normal labor, replicate 18 of 26
normal
TRUE
GSM225490
Placenta tissue from patient with normal labor, replicate 19 of 26
normal
TRUE
GSM225491
Placenta tissue from patient with normal labor, replicate 20 of 26
normal
TRUE
GSM225492
Placenta tissue from patient with normal labor, replicate 21 of 26
normal
TRUE
GSM225493
Placenta tissue from patient with normal labor, replicate 22 of 26
normal
TRUE
GSM225494
Placenta tissue from patient with normal labor, replicate 23 of 26
normal
TRUE
GSM225495
Placenta tissue from patient with normal labor, replicate 24 of 26
normal
TRUE
GSM225496
Placenta tissue from patient with normal labor, replicate 25 of 26
normal
TRUE
GSM225497
Placenta tissue from patient with normal labor, replicate 26 of 26
normal
TRUE
GSM225498
Placenta tissue from patients with severe preeclampsia, replicate 2 of 17
preeclampsia
TRUE
GSM225499
Placenta tissue from patients with severe preeclampsia, replicate 3 of 17
preeclampsia
TRUE
GSM225500
Placenta tissue from patients with severe preeclampsia, replicate 4 of 17
preeclampsia
TRUE
GSM225501
Placenta tissue from patients with severe preeclampsia, replicate 5 of 17
preeclampsia
TRUE
GSM225502
Placenta tissue from patients with severe preeclampsia, replicate 6 of 17
preeclampsia
TRUE
GSM225503
Placenta tissue from patients with severe preeclampsia, replicate 7 of 17
preeclampsia
TRUE
GSM225504
Placenta tissue from patients with severe preeclampsia, replicate 8 of 17
preeclampsia
TRUE
GSM225505
Placenta tissue from patients with severe preeclampsia, replicate 9 of 17
preeclampsia
TRUE
GSM225506
Placenta tissue from patients with severe preeclampsia, replicate 10 of 17
preeclampsia
TRUE
GSM225507
Placenta tissue from patients with severe preeclampsia, replicate 11 of 17
preeclampsia
TRUE
GSM225508
Placenta tissue from patients with severe preeclampsia, replicate 12 of 17
preeclampsia
TRUE
GSM225509
Placenta tissue from patients with severe preeclampsia, replicate 13 of 17
preeclampsia
TRUE
GSM225510
Placenta tissue from patients with severe preeclampsia, replicate 14 of 17
preeclampsia
TRUE
GSM225511
Placenta tissue from patients with severe preeclampsia, replicate 15 of 17
preeclampsia
TRUE
GSM225512
Placenta tissue from patients with severe preeclampsia, replicate 16 of 17
preeclampsia
TRUE
GSM225513
Placenta tissue from patients with severe preeclampsia, replicate 17 of 17
preeclampsia
TRUE

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