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Clinical

Gene expression profiling for placentas from pre-eclamptic, unexplained FGR and normal pregnancies GSE24129

Purpose

It has been well documented that pre-eclampsia and unexplained fetal growth restriction (FGR) has a common etiological background, but little is known about the linkage al the molecular level.we have performed global gene expression profiling by oligonucleotide microarrays for placentas from pre-eclamptic, unexplained FGR and normal pregnancies to further elucidate the mechanisms underlying the development of these two disorders.

Hypothesis

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Experimental Design

The total number of samples used was 8 from pre-eclampsia, 8 from normotensive pregnancies with FGR and 8 from those without FGR.

Experimental Variables

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Controls

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Methods

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Additional Information

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Microarray
Affymetrix HuGene 1.0 ST v1
24 Samples Loaded: 24
Human (Homo sapiens)
placenta
pre-eclampsia, Fetal Growth Restriction
Sample Set Spreadsheet
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Samples Preview
Sample ID !Sample_title tissue disease state !Sample Title Disease state
GSM594041 Normotensive control pregnancy_1 Placenta Normotensive control pregnancy Normotensive control pregnancy_1 Normotensive control pregnancy
GSM594042 Normotensive control pregnancy_2 Placenta Normotensive control pregnancy Normotensive control pregnancy_2 Normotensive control pregnancy
GSM594043 Normotensive control pregnancy_3 Placenta Normotensive control pregnancy Normotensive control pregnancy_3 Normotensive control pregnancy
GSM594044 Normotensive control pregnancy_4 Placenta Normotensive control pregnancy Normotensive control pregnancy_4 Normotensive control pregnancy
GSM594045 Normotensive control pregnancy_5 Placenta Normotensive control pregnancy Normotensive control pregnancy_5 Normotensive control pregnancy
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File
sampleset4000011_sampleannotations_grouped.csv
Sample Set Spreadsheet
Log2 Transformed
Raw Signal
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Sample ID !Sample Title Tissue Disease state !Sample Title Disease state Group
GSM594041
Normotensive control pregnancy_1
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_1
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594042
Normotensive control pregnancy_2
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_2
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594043
Normotensive control pregnancy_3
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_3
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594044
Normotensive control pregnancy_4
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_4
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594045
Normotensive control pregnancy_5
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_5
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594046
Normotensive control pregnancy_6
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_6
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594047
Normotensive control pregnancy_7
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_7
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594048
Normotensive control pregnancy_8
Placenta
Normotensive control pregnancy
Normotensive control pregnancy_8
Normotensive control pregnancy
Normotensive control pregnancy-Placenta
GSM594049
Fetal growth restriction (FGR) _1
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _1
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594050
Fetal growth restriction (FGR) _2
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _2
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594051
Fetal growth restriction (FGR) _3
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _3
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594052
Fetal growth restriction (FGR) _4
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _4
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594053
Fetal growth restriction (FGR) _5
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _5
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594054
Fetal growth restriction (FGR) _6
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _6
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594055
Fetal growth restriction (FGR) _7
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _7
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594056
Fetal growth restriction (FGR) _8
Placenta
Fetal growth restriction (FGR)
Fetal growth restriction (FGR) _8
Fetal growth restriction
Fetal growth restriction -Placenta
GSM594057
Pre-eclampsia_1
Placenta
Pre-eclampsia
Pre-eclampsia_1
Pre-eclampsia
Pre-eclampsia-Placenta
GSM594058
Pre-eclampsia_2
Placenta
Pre-eclampsia
Pre-eclampsia_2
Pre-eclampsia
Pre-eclampsia-Placenta
GSM594059
Pre-eclampsia_3
Placenta
Pre-eclampsia
Pre-eclampsia_3
Pre-eclampsia
Pre-eclampsia-Placenta
GSM594060
Pre-eclampsia_4
Placenta
Pre-eclampsia
Pre-eclampsia_4
Pre-eclampsia
Pre-eclampsia-Placenta
GSM594061
Pre-eclampsia_5
Placenta
Pre-eclampsia
Pre-eclampsia_5
Pre-eclampsia
Pre-eclampsia-Placenta
GSM594062
Pre-eclampsia_6
Placenta
Pre-eclampsia
Pre-eclampsia_6
Pre-eclampsia
Pre-eclampsia-Placenta
GSM594063
Pre-eclampsia_7
Placenta
Pre-eclampsia
Pre-eclampsia_7
Pre-eclampsia
Pre-eclampsia-Placenta
GSM594064
Pre-eclampsia_8
Placenta
Pre-eclampsia
Pre-eclampsia_8
Pre-eclampsia
Pre-eclampsia-Placenta

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